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PTH1R Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PTH1R Antibody (N-Term) AP22170a
    Anti-PTH1R Antibody (N-Term) at 1:2000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 66 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q03431
Other Accession Q5RAQ1
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 66361 Da
Additional info
Gene ID 5745
Other Names Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R, PTHR, PTHR1
Target/Specificity This PTH1R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 52-86 amino acids from human PTH1R.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTH1R Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTH1R
Synonyms PTHR, PTHR1
Function This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in most tissues. Most abundant in kidney, bone and liver
Research Areas

BACKGROUND

This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

REFERENCES

Schipani E.,et al.Endocrinology 132:2157-2165(1993).
Schneider H.,et al.Eur. J. Pharmacol. 246:149-155(1993).
Schipani E.,et al.J. Clin. Endocrinol. Metab. 80:1611-1621(1995).
Levine M.A.,et al.Submitted (NOV-1994) to the EMBL/GenBank/DDBJ databases.
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

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