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G6PC3 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - G6PC3 Antibody (C-Term) AP22167b
    All lanes : Anti-G6PC3 Antibody (C-Term) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: A549 whole cell lysate Lane 3: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9BUM1
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 38735 Da
Additional info
Gene ID 92579
Other Names Glucose-6-phosphatase 3, G-6-Pase 3, G6Pase 3, 3.1.3.9, Glucose-6-phosphatase beta, G6Pase-beta, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, G6PC3, UGRP
Target/Specificity This G6PC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 215-246 amino acids from human G6PC3.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsG6PC3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name G6PC3
Synonyms UGRP
Function Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed. Highly expressed in skeletal muscle, at intermediate levels in heart, brain, placenta, kidney, colon, thymus, spleen and pancreas. Also detected in testis, prostate, ovary, liver, lung, small intestine and peripheral blood lymphocytes.
Research Areas

BACKGROUND

Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function.

REFERENCES

Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Martin C.C.,et al.J. Mol. Endocrinol. 29:205-222(2002).
Guionie O.,et al.FEBS Lett. 551:159-164(2003).
Shieh J.-J.,et al.J. Biol. Chem. 278:47098-47103(2003).
Ghosh A.,et al.J. Biol. Chem. 279:12479-12483(2004).

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