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>   首页   >   产品   >   一抗   >   CHTF8 Antibody (C-Term)   

CHTF8 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CHTF8 Antibody (C-Term) AP22136b
    All lanes : Anti-CHTF8 Antibody (C-Term) at 1:2000 dilution Lane 1: U-2OS whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P0CG12
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 51391 Da
Additional info
Other Names Chromosome transmission fidelity protein 8 homolog isoform 2, Decreased expression in renal and prostate cancer protein, CHTF8, DERPC
Target/Specificity This CHTF8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 344-377 amino acids from human CHTF8.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHTF8 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHTF8
Synonyms DERPC
Function Potential tumor suppressor. Inhibits prostate tumor cell growth, when overexpressed.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed, with abundant expression in kidney, skeletal muscle, testis, liver, ovary, and heart and moderate expression in prostate. Expression is significantly reduced in renal and prostate tumors. No differential expression in breast cancer cells, between lobular carcinoma and normal lobules.

BACKGROUND

Potential tumor suppressor. Inhibits prostate tumor cell growth, when overexpressed.

REFERENCES

Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Sun M.,et al.Mol. Med. 8:655-663(2002).
Green A.R.,et al.Breast Cancer Res. Treat. 113:59-66(2009).

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