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CHRM3 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CHRM3 Antibody (Center) AP22121c
    All lanes : Anti-CHRM3 Antibody (Center) at 1:16000 dilution Lane 1: KG-1 whole cell lysate Lane 2: SW620 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 66 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P20309
Other Accession P41984, P49578, Q9N2A3, Q9ERZ3, Q9N2A4, P11483, Q9N2A2, P08483
Reactivity Human
Predicted Bovine, Chicken, Mouse, Pig, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 66128 Da
Additional info
Gene ID 1131
Other Names Muscarinic acetylcholine receptor M3, CHRM3
Target/Specificity This CHRM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 233-264 amino acids from the Central region of human CHRM3.
Dilution WB~~1:16000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHRM3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHRM3
Function The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein
Research Areas

BACKGROUND

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

REFERENCES

Peralta E.G.,et al.EMBO J. 6:3923-3929(1987).
Bonner T.I.,et al.Neuron 1:403-410(1988).
Kitano T.,et al.Mol. Biol. Evol. 21:936-944(2004).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

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