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>   首页   >   产品   >   一抗   >   代谢   >   NT5M Antibody (Center)   

NT5M Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - NT5M Antibody (Center) AP22117c
    All lanes : Anti-NT5M Antibody (Center) at 1:2000 dilution Lane 1: A549 whole cell lysate Lane 2: RPMI-8226 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NPB1
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 25862 Da
Additional info
Gene ID 56953
Other Names 5'(3')-deoxyribonucleotidase, mitochondrial, 5', 3'-nucleotidase, mitochondrial, 3.1.3.-, Deoxy-5'-nucleotidase 2, dNT-2, NT5M, DNT2
Target/Specificity This NT5M antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-90 amino acids from the Central region of human NT5M.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNT5M Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NT5M
Synonyms DNT2
Function Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas
Research Areas

BACKGROUND

Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.

REFERENCES

Rampazzo C.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:8239-8244(2000).
Rinaldo-Matthis A.,et al.Nat. Struct. Biol. 9:779-787(2002).

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