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ERVK-21 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ERVK-21 Antibody (Center) AP22081c
    Anti-ERVK-21 Antibody (Center) at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 79 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P61565
Other Accession Q902F9, O42043, O71037, P61566, P61570, Q9HDB8, Q69384, P61567, Q902F8, Q9UKH3, P63135
Reactivity Human
Predicted Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 79236 Da
Additional info
Other Names Endogenous retrovirus group K member 21 Env polyprotein, EnvK1 protein, Envelope polyprotein, HERV-K_12q14.1 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVK-21
Target/Specificity This ERVK-21 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-302 amino acids from the Central region of human ERVK-21.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsERVK-21 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERVK-21
Function Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.
Cellular Location Transmembrane protein: Cell membrane; Single-pass type I membrane protein Endogenous retrovirus group K member 21 Env polyprotein: Virion
Research Areas

BACKGROUND

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.

REFERENCES

Scherer S.E.,et al.Nature 440:346-351(2006).
de Parseval N.,et al.J. Virol. 77:10414-10422(2003).
Blaise S.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:13013-13018(2003).
Wang-Johanning F.,et al.Oncogene 22:1528-1535(2003).

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