|Application ||WB, E|
|Other Accession||Q902F9, O42043, O71037, P61566, P61570, Q9HDB8, Q69384, P61567, Q902F8, Q9UKH3, P63135|
|Calculated MW||79236 Da|
|Other Names||Endogenous retrovirus group K member 21 Env polyprotein, EnvK1 protein, Envelope polyprotein, HERV-K_12q14.1 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVK-21|
|Target/Specificity||This ERVK-21 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-302 amino acids from the Central region of human ERVK-21.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ERVK-21 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.|
|Cellular Location||Transmembrane protein: Cell membrane; Single-pass type I membrane protein Endogenous retrovirus group K member 21 Env polyprotein: Virion|
Provided below are standard protocols that you may find useful for product applications.
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.
Scherer S.E.,et al.Nature 440:346-351(2006).
de Parseval N.,et al.J. Virol. 77:10414-10422(2003).
Blaise S.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:13013-13018(2003).
Wang-Johanning F.,et al.Oncogene 22:1528-1535(2003).