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>   首页   >   产品   >   一抗   >   NT5C Antibody (N-Term)   

NT5C Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - NT5C Antibody (N-Term) AP22072a
    All lanes : Anti-NT5C Antibody (N-Term) at 1:2000 dilution Lane 1: Raji whole cell lysate Lane 2: U-251 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 23 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q8TCD5
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 23383 Da
Additional info
Gene ID 30833
Other Names 5'(3')-deoxyribonucleotidase, cytosolic type, 3.1.3.-, Cytosolic 5', 3'-pyrimidine nucleotidase, Deoxy-5'-nucleotidase 1, dNT-1, NT5C, DNT1, UMPH2
Target/Specificity This NT5C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from human NT5C.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNT5C Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NT5C
Synonyms DNT1, UMPH2
Function Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
Cellular Location Cytoplasm.
Tissue Location Detected in skeletal muscle, heart and pancreas.

BACKGROUND

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.

REFERENCES

Rampazzo C.,et al.J. Biol. Chem. 275:5409-5415(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Rampazzo C.,et al.Gene 294:109-117(2002).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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