|Application ||WB, E|
|Calculated MW||23383 Da|
|Other Names||5'(3')-deoxyribonucleotidase, cytosolic type, 3.1.3.-, Cytosolic 5', 3'-pyrimidine nucleotidase, Deoxy-5'-nucleotidase 1, dNT-1, NT5C, DNT1, UMPH2|
|Target/Specificity||This NT5C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from human NT5C.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.|
|Tissue Location||Detected in skeletal muscle, heart and pancreas.|
Provided below are standard protocols that you may find useful for product applications.
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
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Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).