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DPYD Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - DPYD Antibody (C-Term) AP22058b
    Anti-DPYD Antibody (C-Term) at 1:2000 dilution + mouse lung lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 111 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q12882
Other Accession Q5R895
Reactivity Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 111401 Da
Additional info
Gene ID 1806
Other Names Dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, 1.3.1.2, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, DPYD
Target/Specificity This DPYD antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 841-875 amino acids from human DPYD.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDPYD Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPYD
Function Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
Cellular Location Cytoplasm.
Tissue Location Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells
Research Areas

BACKGROUND

Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.

REFERENCES

Yokota H.,et al.J. Biol. Chem. 269:23192-23196(1994).
Johnson M.R.,et al.Cancer Res. 57:1660-1663(1997).
Ogura K.,et al.Cancer Lett. 122:107-113(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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