|Application ||WB, E|
|Calculated MW||62217 Da|
|Other Names||N-acetylmuramoyl-L-alanine amidase, 220.127.116.11, Peptidoglycan recognition protein 2, Peptidoglycan recognition protein long, PGRP-L, PGLYRP2, PGLYRPL, PGRPL|
|Target/Specificity||This PGLYRP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-107 amino acids from human PGLYRP2.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PGLYRP2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.|
|Cellular Location||Secreted. Membrane.|
|Tissue Location||Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum.|
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Liu C.,et al.J. Biol. Chem. 276:34686-34694(2001).
Yamada S.,et al.Oncogene 23:5901-5911(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.