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TAX1BP3 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TAX1BP3 Antibody (C-Term) AP22005b
    Anti-TAX1BP3 Antibody (C-Term) at 1:2000 dilution + HT-1080 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 14 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O14907
Other Accession Q9DBG9, Q4QQV1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 13735 Da
Additional info
Gene ID 30851
Other Names Tax1-binding protein 3, Glutaminase-interacting protein 3, Tax interaction protein 1, TIP-1, Tax-interacting protein 1, TAX1BP3 (HGNC:30684)
Target/Specificity This TAX1BP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 71-103 amino acids from human TAX1BP3.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAX1BP3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAX1BP3 (HGNC:30684)
Function May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
Cellular Location Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins
Tissue Location Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes.
Research Areas

BACKGROUND

May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.

REFERENCES

Rousset R.,et al.Oncogene 16:643-654(1998).
Touchman J.W.,et al.Genome Res. 10:165-173(2000).
Olalla L.,et al.FEBS Lett. 488:116-122(2001).
Honore B.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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