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ERVK-7 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ERVK-7 Antibody (C-Term) AP22000b
    Anti-ERVK-7 Antibody (C-Term) at 1:2000 dilution + human placenta lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 67 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P61567
Other Accession Q902F9, O42043, O71037, P61565, P61566, Q69384, Q902F8, Q9UKH3, P63135
Reactivity Human
Predicted Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 66649 Da
Additional info
Other Names Endogenous retrovirus group K member 7 Env polyprotein, Envelope polyprotein, HERV-K(III) envelope protein, HERV-K102 envelope protein, HERV-K_1q22 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVK-7
Target/Specificity This ERVK-7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 457-491 amino acids from human ERVK-7.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsERVK-7 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERVK-7
Function Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).
Cellular Location Virion.
Tissue Location Expressed in lung, placenta, testis and peripheral blood lymphocytes.
Research Areas

BACKGROUND

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).

REFERENCES

Barbulescu M.,et al.Curr. Biol. 9:861-868(1999).
Sugimoto J.,et al.Genomics 72:137-144(2001).
Wang-Johanning F.,et al.Oncogene 22:1528-1535(2003).

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