|Application ||WB, E|
|Calculated MW||173103 Da|
|Other Names||Synaptojanin-1, Synaptic inositol 1, 5-trisphosphate 5-phosphatase 1, SYNJ1, KIAA0910|
|Target/Specificity||This SYNJ1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1517-1551 amino acids from the C-terminal region of human SYNJ1.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SYNJ1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis.|
|Tissue Location||Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells Isoform 2 is very abundant in nerve terminals|
Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis.
Haffner C.,et al.FEBS Lett. 419:175-180(1997).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Hattori M.,et al.Nature 405:311-319(2000).
Cestra G.,et al.J. Biol. Chem. 274:32001-32007(1999).