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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   MC3R Antibody (C-term)   

MC3R Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - MC3R Antibody (C-term) AP21431b
    All lanes : Anti-MC3R Antibody (C-term) at 1:2000 dilution Lane 1: mouse large intestine lysates Lane 2: human placenta lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 36 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P41968
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 36043 Da
Additional info
Gene ID 4159
Other Names Melanocortin receptor 3, MC3-R, MC3R
Target/Specificity This MC3R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 301-335 amino acids from the C-terminal region of human MC3R.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMC3R Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MC3R
Function Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Brain, placental, and gut tissues.
Research Areas

BACKGROUND

Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.

REFERENCES

Gantz I.,et al.J. Biol. Chem. 268:8246-8250(1993).
Kopatz S.A.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Deloukas P.,et al.Nature 414:865-871(2001).
Tarnow P.,et al.Obes. Facts 5:45-51(2012).
Lee Y.-S.,et al.J. Clin. Endocrinol. Metab. 87:1423-1426(2002).

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