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PBRM1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - PBRM1 Antibody (C-term) AP21362b
    All lanes : Anti-PBRM1 Antibody (C-term) at 1:2000 dilution Lane 1: F9 whole cell lysates Lane 2: NCCIT whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 193 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q86U86
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 192948 Da
Additional info
Gene ID 55193
Other Names Protein polybromo-1, hPB1, BRG1-associated factor 180, BAF180, Polybromo-1D, PBRM1, BAF180, PB1
Target/Specificity This PBRM1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1121-1155 amino acids from the C-terminal region of human PBRM1.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPBRM1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PBRM1
Synonyms BAF180, PB1
Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.
Cellular Location Nucleus.
Tissue Location Widely expressed.
Research Areas

BACKGROUND

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.

REFERENCES

Xue Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:13015-13020(2000).
Horikawa I.,et al.DNA Seq. 13:211-215(2002).
Sekine I.,et al.Oncogene 24:2735-2738(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lemon B.,et al.Nature 414:924-928(2001).

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