|Application ||WB, E|
|Calculated MW||54924 Da|
|Other Names||Archaemetzincin-1, 34--, Archeobacterial metalloproteinase-like protein 1, AMZ1, KIAA1950|
|Target/Specificity||This AMZ1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 65-96 amino acids from the human region of human AMZ1.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AMZ1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2.|
|Tissue Location||Predominantly expressed in heart and liver. Also expressed at lower level in kidney, pancreas and testis Expressed in fetal tissues such as kidney, liver, lung and brain|
Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2.
Diaz-Perales A.,et al.J. Biol. Chem. 280:30367-30375(2005).
Nagase T.,et al.DNA Res. 8:319-327(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).