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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   CCR1 Antibody (C-term)   

CCR1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CCR1 Antibody (C-term) AP21344b
    Anti-CCR1 Antibody (C-term)at 1:2000 dilution + Jurkat whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P32246
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 41173 Da
Additional info
Gene ID 1230
Other Names C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, RANTES-R, CD191, CCR1, CMKBR1, CMKR1, SCYAR1
Target/Specificity This CCR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 343-375 amino acids from the C-terminal region of human CCR1.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR1
Synonyms CMKBR1, CMKR1, SCYAR1
Function Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed in different hematopoietic cells
Research Areas

BACKGROUND

Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.

REFERENCES

Neote K.,et al.Cell 72:415-425(1993).
Gao J.-L.,et al.J. Exp. Med. 177:1421-1427(1993).
Nomura H.,et al.Int. Immunol. 5:1239-1249(1993).
Ko J.,et al.FASEB J. 18:890-892(2004).
Sung H.J.,et al.Exp. Mol. Med. 40:332-338(2008).

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