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>   首页   >   产品   >   一抗   >   细胞生物学   >   AKAP8 Antibody (Center)   

AKAP8 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - AKAP8 Antibody (Center) AP21342c
    Anti-AKAP8 Antibody (Center)at 1:2000 dilution + Hela whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O43823
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 76108 Da
Additional info
Gene ID 10270
Other Names A-kinase anchor protein 8, AKAP-8, A-kinase anchor protein 95 kDa, AKAP 95, AKAP8, AKAP95
Target/Specificity This AKAP8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 395-430 amino acids from the Central region of human AKAP8.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAKAP8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKAP8
Synonyms AKAP95
Function Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).
Cellular Location Nucleus matrix. Note=Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis
Tissue Location Highly expressed in heart, liver, skeletal muscle, kidney and pancreas
Research Areas

BACKGROUND

Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).

REFERENCES

Eide T.,et al.Exp. Cell Res. 238:305-316(1998).
Grimwood J.,et al.Nature 428:529-535(2004).
Olsen J.V.,et al.Cell 127:635-648(2006).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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