|Application ||WB, E|
|Calculated MW||61068 Da|
|Other Names||Inositol-3-phosphate synthase 1, IPS 1, Myo-inositol 1-phosphate synthase, MI-1-P synthase, MIP synthase, hIPS, Myo-inositol 1-phosphate synthase A1, hINO1, ISYNA1, INO1|
|Target/Specificity||This ISYNA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 541-574 amino acids from the C-terminal region of human ISYNA1.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ISYNA1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.|
|Tissue Location||Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.|
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
Guan G.,et al.Arch. Biochem. Biophys. 417:251-259(2003).
Parthasarathy L.K.,et al.Subcell. Biochem. 39:293-314(2006).
Zhou Y.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).