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>   首页   >   产品   >   一抗   >   神经科学   >   NLGN3 Antibody (C-term)   

NLGN3 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - NLGN3 Antibody (C-term) AP21311b
    All lanes : Anti-NLGN3 Antibody (C-term) at 1:1000 dilution Lane 1: rat brain lysates Lane 2: mouse brain lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 94 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NZ94
Reactivity Mouse, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 93895 Da
Additional info
Gene ID 54413
Other Names Neuroligin-3, Gliotactin homolog, NLGN3, KIAA1480, NL3
Target/Specificity This NLGN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 651-685 amino acids from the C-terminal region of human NLGN3.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNLGN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NLGN3
Synonyms KIAA1480, NL3
Function Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.
Tissue Location Expressed in the blood vessel walls (at protein level). Detected in throughout the brain and in spinal cord. Detected in brain, and at lower levels in pancreas islet beta cells.
Research Areas

BACKGROUND

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).

REFERENCES

Philibert R.A.,et al.Gene 246:303-310(2000).
Rissone A.,et al.Dev. Dyn. 239:688-702(2010).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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