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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   CNR1 Antibody (C-term)   

CNR1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CNR1 Antibody (C-term) AP21304b
    Anti-CNR1 Antibody (C-term)at 1:2000 dilution + A431 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 53 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P21554
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 52858 Da
Additional info
Gene ID 1268
Other Names Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR
Target/Specificity This CNR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 433-468 amino acids from the C-terminal region of human CNR1.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNR1
Synonyms CNR
Function Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Widely expressed.
Research Areas

BACKGROUND

Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.

REFERENCES

Gerard C.,et al.Nucleic Acids Res. 18:7142-7142(1990).
Gerard C.,et al.Biochem. J. 279:129-134(1991).
Shire D.,et al.J. Biol. Chem. 270:3726-3731(1995).
Ryberg E.,et al.FEBS Lett. 579:259-264(2005).
Kathmann M.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.

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