|Application ||IF, WB, E|
|Calculated MW||42123 Da|
|Other Names||Guanine nucleotide-binding protein subunit alpha-11, G alpha-11, G-protein subunit alpha-11, Guanine nucleotide-binding protein G(y) subunit alpha, GNA11, GA11|
|Target/Specificity||This GNA11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 115-146 amino acids from the Central region of human GNA11.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNA11 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.|
|Cellular Location||Cell membrane; Lipid-anchor. Cytoplasm. Note=In testicular cells, expressed exclusively in the cytoplasm|
|Tissue Location||Expressed in testis.|
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.
Jiang M.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:3907-3911(1991).
Bai X.H.,et al.Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).