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>   首页   >   产品   >   一抗   >   其他   >   DBP Antibody (C-term)   

DBP Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - DBP Antibody (C-term) AP21269b
    All lanes : Anti-DBP Antibody (C-term) at 1:2000 dilution Lane 1: HepG2 whole cell lysates Lane 2: MCF-7 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 34 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q10586
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 34349 Da
Additional info
Gene ID 1628
Other Names D site-binding protein, Albumin D box-binding protein, Albumin D-element-binding protein, Tax-responsive enhancer element-binding protein 302, TaxREB302, DBP
Target/Specificity This DBP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 233-266 amino acids from the C-terminal region of human DBP.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDBP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DBP
Function This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity
Research Areas

BACKGROUND

This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.

REFERENCES

Khatib Z.A.,et al.Genomics 23:344-351(1994).
Shutler G.,et al.Genomics 34:334-339(1996).
Yu W.,et al.Genome Res. 7:353-358(1997).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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