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>   首页   >   产品   >   一抗   >   癌症   >   PPAP2B Antibody (N-term)   

PPAP2B Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - PPAP2B Antibody (N-term) AP21245a
    All lanes : Anti-PPAP2B Antibody (N-term) at 1:2000 dilution Lane 1: SW620 whole cell lysates Lane 2: human placenta lysates Lane 3: human kidney lysates Lane 4: human lung lysates Lane 5: rat liver lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 35 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O14495
Reactivity Human, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 35116 Da
Additional info
Gene ID 8613
Other Names Lipid phosphate phosphohydrolase 3, PAP2-beta, Phosphatidate phosphohydrolase type 2b, Phosphatidic acid phosphatase 2b, PAP-2b, PAP2b, Vascular endothelial growth factor and type I collagen-inducible protein, VCIP, PPAP2B, LPP3
Target/Specificity This PPAP2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3~37 amino acids from the N-terminal region of human PPAP2B.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPAP2B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPAP2B
Synonyms LPP3
Function Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed. Highly expressed in heart and placenta
Research Areas

BACKGROUND

Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions.

REFERENCES

Kai M.,et al.J. Biol. Chem. 272:24572-24578(1997).
Roberts R.,et al.J. Biol. Chem. 273:22059-22067(1998).
Humtsoe J.O.,et al.EMBO J. 22:1539-1554(2003).
Leung D.W.,et al.Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Yu W.,et al.Genome Res. 7:353-358(1997).

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