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>   首页   >   产品   >   一抗   >   细胞生物学   >   UBE2G2 Antibody (N-term)   

UBE2G2 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - UBE2G2 Antibody (N-term) AP2123a
    The anti-UBE2G2 Pab (Cat. #AP2123a) is used in Western blot to detect UBE2G2 in Jurkat cell lysate.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P60604
Other Accession P60605, Q17QG5, NP_003334
Reactivity Human
Predicted Mouse, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 7327
Other Names Ubiquitin-conjugating enzyme E2 G2, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2, UBE2G2
Target/Specificity This UBE2G2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human UBE2G2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUBE2G2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2G2
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Involved in endoplasmic reticulum- associated degradation (ERAD).
Research Areas

BACKGROUND

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2G2 is a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle.

REFERENCES

Webster, J.M., et al., J. Biol. Chem. 278(40):38238-38246 (2003).
Katsanis, N., et al., Genomics 51(1):128-131 (1998).
Rose, S.A., et al., Cytogenet. Cell Genet. 83 (1-2), 98-99 (1998).

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