|Application ||IHC-P, WB, E|
|Calculated MW||44230 Da|
|Other Names||Zinc finger protein ubi-d4, Apoptosis response zinc finger protein, BRG1-associated factor 45D, BAF45D, D4, zinc and double PHD fingers family 2, Protein requiem, Dpf2, Baf45d, Req, Ubid4|
|Target/Specificity||This mouse Dpf2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from the N-terminal region of mouse Dpf2.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(Mouse) Dpf2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||Baf45d, Req, Ubid4|
|Function||May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||In embryo, highest levels are seen in brain, eyes, thymus and olfactory epithelium in nose, whereas several other tissues, including the musculoskeletal system, show moderate expression. In adult, higher expression in testis, medium in thymus and spleen, lower in certain parts of the brain as the hippocampus. No expression in adult heart, lung, liver, duodenum and kidney.|
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.
Mertsalov I.B.,et al.Mamm. Genome 11:72-74(2000).
Carninci P.,et al.Science 309:1559-1563(2005).
Gabig T.G.,et al.J. Biol. Chem. 269:29515-29519(1994).
Gabig T.G.,et al.Mamm. Genome 9:660-665(1998).
Lessard J.,et al.Neuron 55:201-215(2007).