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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   TSHR Antibody (Center)   

TSHR Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TSHR Antibody (Center) AP21182c
    Anti-TSHR Antibody (Center) at 1:1000 dilution + mouse liver lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 87 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P16473
Reactivity Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 86830 Da
Additional info
Gene ID 7253
Other Names Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR, LGR3
Target/Specificity This TSHR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 217-252 amino acids from the Central region of human TSHR.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTSHR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSHR
Synonyms LGR3
Function Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in the thyroid.
Research Areas

BACKGROUND

Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).

REFERENCES

Nagayama Y.,et al.Biochem. Biophys. Res. Commun. 165:1184-1190(1989).
Libert F.,et al.Biochem. Biophys. Res. Commun. 165:1250-1255(1989).
Misrahi M.,et al.Biochem. Biophys. Res. Commun. 166:394-403(1990).
Frazier A.L.,et al.Mol. Endocrinol. 4:1264-1276(1990).
Graves P.N.,et al.Biochem. Biophys. Res. Commun. 187:1135-1143(1992).

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