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Mouse Nr5a2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Mouse Nr5a2 Antibody (Center) AP21181c
    All lanes : Anti-Nr5a2 Antibody (Center) at 1:1000 dilution Lane 1: mouse small intestine lysates Lane 2: rat testis lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P45448
Reactivity Mouse, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 64020 Da
Additional info
Gene ID 26424
Other Names Nuclear receptor subfamily 5 group A member 2, Liver receptor homolog 1, LRH-1, Nr5a2, Lrh1
Target/Specificity This Mouse Nr5a2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 200-233 amino acids from the Central region of Mouse Nr5a2.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Nr5a2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Nr5a2
Synonyms Lrh1
Function Binds to promoters containing the sequence element 5'- AACGACCGACCTTGAG-3'. Plays a role in the regulation of gene expression in liver and pancreas. May play a role in embryonic development (By similarity).
Cellular Location Nucleus.
Research Areas
REV-ERBa Regulates CYP7A1 through Repression of Liver Receptor Homolog-1.
Author : Zhang T1,Zhao M1,Lu D1,Wang S1,Yu F1,Guo L1,Wen S2,Wu B3.
Drug Metab Dispos. 2017 Dec 13. pii: dmd.117.078105. doi: 10.1124/dmd.117.078105. [Epub ahead of print]
29237721

BACKGROUND

Binds to promoters containing the sequence element 5'- AACGACCGACCTTGAG-3'. Plays a role in the regulation of gene expression in liver and pancreas. May play a role in embryonic development (By similarity).

REFERENCES

Tugwood J.D.,et al.Submitted (FEB-1992) to the EMBL/GenBank/DDBJ databases.
Sablin E.P.,et al.Mol. Cell 11:1575-1585(2003).
Li Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:9505-9510(2005).

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