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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   HTR1F Antibody (Center)   

HTR1F Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - HTR1F Antibody (Center) AP21174a
    Anti-HTR1F Antibody (Center) at 1:1000 dilution + K562 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 42 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - HTR1F Antibody (Center) AP21174a
    Anti-HTR1F Antibody (Center) at 1:4000 dilution + KG-1 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 42 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P30939
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 41709 Da
Additional info
Gene ID 3355
Other Names 5-hydroxytryptamine receptor 1F, 5-HT-1F, 5-HT1F, Serotonin receptor 1F, HTR1F, HTR1EL
Target/Specificity This HTR1F antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 213-248 amino acids from the Central region of human HTR1F.
Dilution WB~~1:4000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHTR1F Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR1F
Synonyms HTR1EL
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas

BACKGROUND

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

REFERENCES

Lovenberg T.W.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:2184-2188(1993).
Adham N.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:408-412(1993).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Nichols D.E.,et al.Chem. Rev. 108:1614-1641(2008).

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