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>   首页   >   产品   >   一抗   >   精选抗体   >   斑马鱼抗体   >   (DANRE) gpr126 Antibody (C-term)   

(DANRE) gpr126 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - (DANRE) gpr126 Antibody (C-term) AP21136a
    Western blot analysis of lysate from zebra fish brain tissue lysate, using (DANRE) gpr126 Antibody (C-term)(Cat. #AP21136a). AP21136a was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession C6KFA3
Reactivity Zebrafish
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 130813 Da
Additional info
Gene ID 561970
Other Names G-protein coupled receptor 126, gpr126
Target/Specificity This DANRE gpr126 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1135-1169 amino acids from the C-terminal region of DANRE gpr126.
Dilution WB~~1:500
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(DANRE) gpr126 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name gpr126
Function Orphan receptor. Required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels. Required for normal expression of the transcription factors oct6 and krox20 that are required for Schwann cells to initiate myelination.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in Schwann cells of the posterior lateral line nerve and in brain.
Research Areas

BACKGROUND

Orphan receptor. Required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels. Required for normal expression of the transcription factors oct6 and krox20 that are required for Schwann cells to inititate myelination.

REFERENCES

Monk K.R.,et al.Science 325:1402-1405(2009).

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