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>   首页   >   产品   >   一抗   >   神经科学   >   CXCL11 Antibody   

CXCL11 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CXCL11 Antibody AP21132a
    All lanes : Anti-CXCL11 Antibody at 1:2000 dilution Lane 1: human liver lysates Lane 2: human spleen lysates Lane 3: rat liver lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 10 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - CXCL11 Antibody AP21132a
    Western blot analysis of lysate from rat liver tissue lysate, using CXCL11 Antibody(Cat. #AP21132a). AP21132a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O14625
Reactivity Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 10365 Da
Additional info
Gene ID 6373
Other Names C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, CXCL11, ITAC, SCYB11, SCYB9B
Target/Specificity This CXCL11 antibody is generated from a rabbit immunized with a recombinant protein of human CXCL11.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCXCL11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCL11
Synonyms ITAC, SCYB11, SCYB9B
Function Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Cellular Location Secreted.
Tissue Location High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine Also found in epidermal basal layer keratinocytes in skin disorders
Research Areas

BACKGROUND

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

REFERENCES

Rani M.R.S.,et al.J. Biol. Chem. 271:22878-22884(1996).
Jacobs K.A.,et al.Gene 198:289-296(1997).
Cole K.E.,et al.J. Exp. Med. 187:2009-2021(1998).
Tensen C.P.,et al.J. Invest. Dermatol. 112:716-722(1999).
Laich A.M.,et al.J. Interferon Cytokine Res. 19:505-513(1999).

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