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>   首页   >   产品   >   一抗   >   其他   >   Mouse Dnmt3l Antibody (Center)   

Mouse Dnmt3l Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Mouse Dnmt3l Antibody (Center) AP21127a
    Western blot analysis of lysate from mouse heart tissue lysate, using Dnmt3l Antibody (Center)(Cat. #AP21127a). AP21127a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9CWR8
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47993 Da
Additional info
Gene ID 54427
Other Names DNA (cytosine-5)-methyltransferase 3-like, Dnmt3l
Target/Specificity This Mouse Dnmt3l antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 258-290 amino acids from the Central region of mouse Dnmt3l.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Dnmt3l Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dnmt3l
Function Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases.
Cellular Location Nucleus.
Tissue Location Expressed in testis, thymus, ovary, and heart.
Research Areas

BACKGROUND

Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases.

REFERENCES

Aapola U.,et al.Cytogenet. Cell Genet. 92:122-126(2001).
Shaoping X.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Bourc'his D.,et al.Science 294:2536-2539(2001).
Gowher H.,et al.J. Biol. Chem. 280:13341-13348(2005).

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