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>   首页   >   产品   >   一抗   >   神经科学   >   Mouse Lhx1 Antibody (C-term)   

Mouse Lhx1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Mouse Lhx1 Antibody (C-term) AP21094a
    Western blot analysis of lysate from HepG2 cell line, using Lhx1 Antibody (C-term)(Cat. #AP21094a). AP21094a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P63006
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44780 Da
Additional info
Gene ID 16869
Other Names LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein Lim-1, Lhx1, Lim-1, Lim1
Target/Specificity This Mouse Lhx1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 332-365 amino acids from the C-terminal region of Mouse Lhx1.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Lhx1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lhx1
Synonyms Lim-1, Lim1
Function Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:8793615}
Tissue Location In mid to late stage embryos, expressed in a restricted region of mesoderm in the primitive streak. At 7.5 days, expressed in a horseshoe shape at the periphery of the node, as well as along both sides of the adjacent notochord. Also present in presumptive lateral and intermediate mesoderm. Later, expression become progressively restricted to intermediate mesoderm, and the developing excretory system including the pronephric region, mesonephros, nephric duct and metanephros. In the metanephros, strongly expressed in renal vesicles and S-shaped and coma-shaped bodies, as well as in the ureteric bud and its derivatives. Also expressed in the dorsal root ganglia. By stage 10.5, also expressed in regions of the central nervous system in the telencephalon through to the spinal cord. In adults, expressed in the cerebellum/medulla and kidney, and at very low levels in the cerebrum.
Research Areas

BACKGROUND

Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.

REFERENCES

Fujii T.,et al.Dev. Dyn. 199:73-83(1994).
Barnes J.D.,et al.Dev. Biol. 161:168-178(1994).
Li Y.,et al.Mamm. Genome 10:444-446(1999).
Karavanov A.A.,et al.Int. J. Dev. Biol. 40:453-461(1996).
Agulnick A.D.,et al.Nature 384:270-272(1996).

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