|Application ||WB, FC, E|
|Calculated MW||24321 Da|
|Other Names||GTPase ERas, E-Ras, Embryonic stem cell-expressed Ras, Eras|
|Target/Specificity||This Mouse Eras antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 19-52 amino acids from the N-terminal region of mouse Eras.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(Mouse) Eras Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
|Tissue Location||Expressed in several undifferentiated mouse embryonic stem cell lines.|
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells.
Takahashi K.,et al.Nature 423:541-545(2003).
Carninci P.,et al.Science 309:1559-1563(2005).