|Application ||WB, E|
|Calculated MW||23388 Da|
|Other Names||Claudin-6, Skullin, Cldn6|
|Target/Specificity||This mouse Cldn6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 146-180 amino acids from the C-terminal region of mouse Cldn6.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(Mouse) Cldn6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.|
|Cellular Location||Cell junction, tight junction. Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed mostly in embryonic tissues.|
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity).
Morita K.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:511-516(1999).
Troy T.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Itoh M.,et al.J. Cell Biol. 147:1351-1363(1999).