注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 二抗
  • IVD原料
  • 多肽
  • 蛋白
  • 裂解液
  • 免疫试剂盒&组化产品
  • 代理产品
  • 分子生物学产品
>   首页   >   产品   >   一抗   >   干细胞   >   HEMGN Antibody (C-term)   

HEMGN Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
标注"皇冠"的产品,是满足高质量标准的产品。
了解更多...
  • 1 - HEMGN Antibody (C-term) AP21062a
    Anti-HEMGN Antibody (C-term) at 1:2000 dilution + Jurkat whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - HEMGN Antibody (C-term) AP21062a
    Western blot analysis of lysate from Jurkat cell line, using HEMGN Antibody (C-term)(Cat. #AP21062a). AP21062a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
  • 产品详情
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9BXL5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55341 Da
Additional info
Gene ID 55363
Other Names Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR
Target/Specificity This HEMGN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 355-389 amino acids from the C-terminal region of human HEMGN.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHEMGN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HEMGN
Synonyms EDAG, NDR
Function Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Cellular Location Nucleus.
Tissue Location Expressed in hematopoietic precursor cells, thyroid and spermatids (at protein level). Expressed in bone marrow, testis, thymus. Expressed in prostate cancer and ovarian cancer. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia.
Research Areas

BACKGROUND

Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).

REFERENCES

Yang L.V.,et al.Mech. Dev. 104:105-111(2001).
Yang L.V.,et al.Dev. Dyn. 228:606-616(2003).
Li C.Y.,et al.Cell Death Differ. 11:1299-1308(2004).
Liu C.C.,et al.J. Biomed. Sci. 11:104-116(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69369088-1015 market.abgent@wuxiapptec.com.


我要评价