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>   首页   >   产品   >   一抗   >   细胞生物学   >   (Mouse) Gnl3 Antibody (C-term)   

(Mouse) Gnl3 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - (Mouse) Gnl3 Antibody (C-term) AP21045a
    Western blot analysis of lysate from mouse liver tissue lysate, using Gnl3 Antibody (C-term)(Cat. #AP21045a). AP21045a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q8CI11
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60786 Da
Additional info
Gene ID 30877
Other Names Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns
Target/Specificity This Mouse Gnl3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 450-483 amino acids from the C-terminal region of mouse Gnl3.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(Mouse) Gnl3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Gnl3
Synonyms Ns
Function May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Cellular Location Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus
Tissue Location Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells
Research Areas

BACKGROUND

May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.

REFERENCES

Tsai R.Y.L.,et al.Genes Dev. 16:2991-3003(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
Trost M.,et al.Immunity 30:143-154(2009).
Meng L.,et al.Oncogene 30:1716-1726(2011).

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