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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   HCRTR1 Antibody (Center)   

HCRTR1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - HCRTR1 Antibody (Center) AP21007a
    Western blot analysis of lysate from human brain tissue lysate, using HCRTR1 Antibody (Center)(Cat. #AP21007a). AP21007a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O43613
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47536 Da
Additional info
Gene ID 3061
Other Names Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1, HCRTR1
Target/Specificity This HCRTR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 256-291 amino acids from the Central region of human HCRTR1.
Dilution WB~~1:500-1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHCRTR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HCRTR1
Function Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas

BACKGROUND

Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).

REFERENCES

Sakurai T.,et al.Cell 92:573-585(1998).
Peyron C.,et al.Nat. Med. 6:991-997(2000).
Olafsdottir B.R.,et al.Neurology 57:1896-1899(2001).
Yeager M.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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