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>   首页   >   产品   >   一抗   >   神经科学   >   MSI1 Antibody (Center)   

MSI1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - MSI1 Antibody (Center) AP21004a
    Western blot analysis of lysate from SH-SY5Y cell line, using MSI1 Antibody (Center)(Cat. #AP21004a). AP21004a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O43347
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39125 Da
Additional info
Gene ID 4440
Other Names RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
Target/Specificity This MSI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-176 amino acids from the Central region of human MSI1.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSI1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSI1
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Research Areas

BACKGROUND

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

REFERENCES

Good P.,et al.Genomics 52:382-384(1998).
Scherer S.E.,et al.Nature 440:346-351(2006).
Shu H.-J.,et al.Biochem. Biophys. Res. Commun. 293:150-154(2002).
Okano H.,et al.J. Cell Sci. 115:1355-1359(2002).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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