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>   首页   >   产品   >   一抗   >   心血管   >   (Mouse) Jag1 Antibody (C-term)   

(Mouse) Jag1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - (Mouse) Jag1 Antibody (C-term) AP20997c
    Western blot analysis of lysate from rat lung tissue lysate, using Jag1 Antibody (C-term)(Cat. #AP20997c). AP20997c was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9QXX0
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 134164 Da
Additional info
Gene ID 16449
Other Names Protein jagged-1, Jagged1, CD339, Jag1
Target/Specificity This (Mouse) Jag1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1103-1137 amino acids from the C-terminal region of mouse Jag1.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(Mouse) Jag1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Jag1
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed in many tissues, with highest expression in brain, heart, muscle and thymus
Research Areas

BACKGROUND

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.

REFERENCES

Shimizu K.,et al.J. Biol. Chem. 274:32961-32969(1999).
Loomes K.M.,et al.Hum. Mol. Genet. 8:2443-2449(1999).

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