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>   首页   >   产品   >   一抗   >   免疫学   >   CXCL16 Antibody (Center)   

CXCL16 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CXCL16 Antibody (Center) AP20991a
    Western blot analysis of lysates from human spleen, human lung tissue lysate (from left to right), using CXCL16 Antibody (Center)(Cat. #AP20991a). AP20991a was diluted at 1:500 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9H2A7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27579 Da
Additional info
Gene ID 58191
Other Names C-X-C motif chemokine 16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SR-PSOX, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, CXCL16, SCYB16, SRPSOX
Target/Specificity This CXCL16 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-183 amino acids from the Central region of human CXCL16.
Dilution WB~~1:500
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCXCL16 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCL16
Synonyms SCYB16, SRPSOX
Function Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Cellular Location Cell membrane; Single-pass type I membrane protein. Secreted. Note=Also exists as a soluble form
Tissue Location Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus Weak expression in heart and liver and no expression in brain and bone marrow
Research Areas

BACKGROUND

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

REFERENCES

Matloubian M.,et al.Nat. Immunol. 1:298-304(2000).
Wilbanks A.,et al.J. Immunol. 166:5145-5154(2001).
Shimaoka T.,et al.J. Biol. Chem. 275:40663-40666(2000).
Livingston R.J.,et al.Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).

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