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>   首页   >   产品   >   一抗   >   干细胞   >   IHH Antibody (C-term)   

IHH Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - IHH Antibody (C-term) AP20973c
    Western blot analysis of lysates from mouse F9, mouse NIH/3T3 cell line, human kidney, human lung, mouse brain, mouse rectum tissue (from left to right), using IHH Antibody (C-term)(Cat. #AP20973c). AP20973c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q14623
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45251 Da
Additional info
Gene ID 3549
Other Names Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
Target/Specificity This IHH antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 397-431 amino acids from the C-terminal region of human IHH.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIHH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IHH
Function Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).
Cellular Location Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. Cell membrane.
Tissue Location Expressed in embryonic lung, and in adult kidney and liver
Research Areas

BACKGROUND

Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).

REFERENCES

Tate G.,et al.J. Biochem. Mol. Biol. Biophys. 4:27-34(2000).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Marigo V.,et al.Genomics 28:44-51(1995).
Chang D.T.,et al.Development 120:3339-3353(1994).
Pepinsky R.B.,et al.J. Biol. Chem. 273:14037-14045(1998).

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