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>   首页   >   产品   >   一抗   >   神经科学   >   (Mouse) Msi1 Antibody (Center)   

(Mouse) Msi1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - (Mouse) Msi1 Antibody (Center) AP20967a
    Western blot analysis of lysates from SH-SY5Y, Neuro-2a cell line (from left to right), using (Mouse) Msi1 Antibody (Center)(Cat. #AP20967a). AP20967a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q61474
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39119 Da
Additional info
Gene ID 17690
Other Names RNA-binding protein Musashi homolog 1, Musashi-1, Msi1, Msi1h
Target/Specificity This mouse Msi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-113 amino acids from the Central region of mouse Msi1.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(Mouse) Msi1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Msi1
Synonyms Msi1h
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Cellular Location Cytoplasm. Nucleus
Tissue Location Detected in olfactory bulb, brain stem, small intestine, and at low levels in brain cortex, hippocampus and ovary. Detected in neural progenitor cells, including neural stem cells.
Research Areas

BACKGROUND

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

REFERENCES

Sakakibara S.,et al.Dev. Biol. 176:230-242(1996).
Carninci P.,et al.Science 309:1559-1563(2005).
Imai T.,et al.Mol. Cell. Biol. 21:3888-3900(2001).
Sakakibara S.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:15194-15199(2002).
Nagata T.,et al.J. Mol. Biol. 287:315-330(1999).

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