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>   首页   >   产品   >   一抗   >   癌症   >   INSRR Antibody (Center)   

INSRR Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - INSRR Antibody (Center) AP20928a
    Anti-INSRR Antibody (Center) at 1:4000 dilution + MCF-7 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 144 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 14 - INSRR Antibody (Center) AP20928a
    Immunohistochemical analysis of paraffin-embedded H. breast carcinoma section using INSRR Antibody (Center)(Cat#AP20928a). AP20928a was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • 14 - INSRR Antibody (Center) AP20928a
    Immunohistochemical analysis of paraffin-embedded H. kidney section using INSRR Antibody (Center)(Cat#AP20928a). AP20928a was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • 1 - INSRR Antibody (Center) AP20928a
    Western blot analysis of lysates from A549, Hela, MCF-7, SH-SY5Y, SW480 cell line (from left to right), using INSRR Antibody (Center)(Cat. #AP20928a). AP20928a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P14616
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 143720 Da
Additional info
Gene ID 3645
Other Names Insulin receptor-related protein, IRR, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, INSRR, IRR
Target/Specificity This INSRR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 668-702 amino acids from the Central region of human INSRR.
Dilution WB~~1:1000
IHC-P~~1:25
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsINSRR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INSRR
Synonyms IRR
Function Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas

BACKGROUND

Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

REFERENCES

Haenze J.,et al.Horm. Metab. Res. 31:77-79(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Shier P.,et al.J. Biol. Chem. 264:14605-14608(1989).
Greenman C.,et al.Nature 446:153-158(2007).

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