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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   CCR2 Antibody (C-term)   

CCR2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CCR2 Antibody (C-term) AP20915c
    All lanes : Anti-CCR2 Antibody (C-term) at 1:2000 dilution Lane 1: THP-1 whole cell lysate Lane 2: HACAT whole cell lysate Lane 3: K562 whole cell lysate Lane 4: U266B1 whole cell lysate Lane 5: Human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 42 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P41597
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 729230
Other Names C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, Monocyte chemoattractant protein 1 receptor, MCP-1-R, CD192, CCR2, CMKBR2
Target/Specificity This CCR2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 336-369 amino acids from the C-terminal region of human CCR2.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCR2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR2
Synonyms CMKBR2
Function Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas

BACKGROUND

Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection.

REFERENCES

Charo I.F.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:2752-2756(1994).
Yamagami S.,et al.Biochem. Biophys. Res. Commun. 202:1156-1162(1994).
Wong L.-M.,et al.J. Biol. Chem. 272:1038-1045(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).

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