|Application ||WB, E|
|Calculated MW||59307 Da|
|Other Names||Transcription factor GATA-6, GATA-binding factor 6, Gata6|
|Target/Specificity||This Mouse Gata6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 485-518 amino acids from the C-terminal region of human Mouse Gata6.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Gata6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator that regulates SEMA3C and PLXNA2. Involved in gene regulation specifically in the gastric epithelium (By similarity). Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343).|
|Tissue Location||Expressed in myocardium, vascular smooth muscle, gut epithelium, and osteoclasts|
Transcriptional activator that regulates SEMA3C and PLXNA2. Involved in gene regulation specifically in the gastric epithelium (By similarity).
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Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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