|Application ||WB, E|
|Calculated MW||52729 Da|
|Other Names||Neuronal acetylcholine receptor subunit beta-3, CHRNB3|
|Target/Specificity||This CHRNB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-200 amino acids from the Central region of human CHRNB3.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CHRNB3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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