|Application ||WB, E|
|Calculated MW||70404 Da|
|Other Names||Heat shock 70 kDa protein 1-like;|
|Target/Specificity||This HSPA1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-603 amino acids from the C-terminal region of human HSPA1L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HSPA1L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.