|Application ||WB, E|
|Calculated MW||43165 Da|
|Other Names||E3 ubiquitin-protein ligase RNF149, 632-, DNA polymerase-transactivated protein 2, RING finger protein 149, RNF149, DNAPTP2|
|Target/Specificity||This RNF149 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human RNF149.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RNF149 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.|
|Cellular Location||Membrane; Single-pass membrane protein|
Provided below are standard protocols that you may find useful for product applications.
The function of this protein remains unknown.
Low, S.K., et al. PLoS ONE 5 (7), E11824 (2010) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)