|Application ||WB, E|
|Other Names||Protein disulfide-isomerase TMX3, Thioredoxin domain-containing protein 10, Thioredoxin-related transmembrane protein 3, TMX3, KIAA1830, TXNDC10|
|Target/Specificity||This TMX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human TMX3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMX3 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed. Expressed in brain, testis, lung, skin, kidney, uterus, bone, stomach, liver, prostate, placenta, eye and muscle.|
Provided below are standard protocols that you may find useful for product applications.
Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase.
Chao, R., et al. PLoS ONE 5 (5), E10565 (2010) :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Haugstetter, J., et al. J. Biol. Chem. 282(46):33859-33867(2007)
Haugstetter, J., et al. J. Biol. Chem. 280(9):8371-8380(2005)