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SLC6A14 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SLC6A14 Antibody (C-term) AP12976B
    All lanes : Anti-SLC6A14 Antibody (C-term) at 1:1000 dilution Lane 1: Human lung lysate Lane 2: Human breast lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 80 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - SLC6A14 Antibody (C-term) AP12976B
    All lanes : Anti-SLC6A14 Antibody (C-term) at 1:1000 dilution Lane 1: Human lung lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: HACAT whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 80 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - SLC6A14 Antibody (C-term) AP12976B
    SLC6A14 Antibody (C-term) (Cat. #AP12976b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SLC6A14 antibody detected the SLC6A14 protein (arrow).
  • 14 - SLC6A14 Antibody (C-term) AP12976B
    SLC6A14 Antibody (C-term) (Cat. #AP12976b)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC6A14 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q9UN76
Other Accession NP_009162.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 72153 Da
Additional info
Gene ID 11254
Other Names Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+), Amino acid transporter ATB0+, Solute carrier family 6 member 14, SLC6A14
Target/Specificity This SLC6A14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-631 amino acids from the C-terminal region of human SLC6A14.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC6A14 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC6A14
Function Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis.
Research Areas

BACKGROUND

This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.

REFERENCES

Bailey, S.D., et al. Diabetes Care (2010) In press :
Corpeleijn, E., et al. Obesity (Silver Spring) 18(7):1369-1377(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Anderson, C.M., et al. J. Physiol. (Lond.) 586 (PT 17), 4061-4067 (2008) :
Eriksson, A., et al. BMC Gastroenterol 8, 34 (2008) :

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